In
chronic Inflammatory pain, the inflammatory chemicals have caused permanent
damage to the chemical receptor and the nerve it feeds. This causes the same
chemicals to damage touch receptors and nerves that normally do not transmit
pain. This results in pain, even to light touch, and the consequence of increased
pain at the Spinal Cord due to wind-up. In this case wind up occurs when normally
non painful touch nerves begin to carry pain to the Central Nervous System.
